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Selenium Supplementation Improved Cardiac Functions by Suppressing DNMT2-Mediated GPX1 Promoter DNA Methylation in AGE-Induced Heart Failure

THE LANDMARK TRIAL PENN STATE, 6 MONTHS, PEER-REVIEWED: A 6-month randomized, double-blind, placebo-controlled human trial of 54 adults at Penn State University (Richie et al., European Journal of Nutrition, 2015) found that oral Setria L-Glutathione at 250 mg/day produced significant increases in whole-blood glutathione levels at 1, 3, and 6 months versus baseline establishing for the first time that oral glutathione is bioavailable in humans

doi: 10.1016/j.ccc.2022.07.006 [PubMed] 36807987 Trinka E