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What are the benefits of an NAG supplement

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In streptozotocin-induced diabetic rats, there was decreased transketolase expression and activity in renal glomeruli, liver, skeletal muscle and RBCs after 12 weeks of diabetes was found associated with progressive increase in the renal clearance of thiamine and increased albuminuria with duration of diabetes, suggesting that abnormal renal handling of thiamine may occur early in the process of impairment of renal function in diabetes [190]

For researchers using oral capsules, taking the compound 30 to 60 minutes before meals in a fasted state may enhance fat oxidation effects, though this recommendation is based on theoretical considerations rather than controlled studies