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In the Philippines, where glutathione has been widely used for skin lightening, the Food and Drug Association of the Philippines FDA has issued a warning about serious side effects from injectable glutathione, including toxic effects on kidneys, liver, and the central nervous system, as well as a life-threatening skin rash

By doing so, it protects tissues from oxidative stress and supports overall cellular health

When cultured in YP20D medium supplemented with 14 mM acrolein, the parental KACC 48331 strain failed to grow, whereas 21 out of 376 UV-induced mutants exhibited detectable growth

A similar inhibition mechanism was also reported by Chawla et al