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To understand if treatment with a GPX4 inhibitor was able to eliminate senescent cells in vivo, we treated mice transduced with an NRAS G12V -expressing transposon with RSL3 (Fig

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There are some limitations acknowledged to this study, including a relatively low sample size (owing to the rarity of IIH) and a short follow-up period, partially mitigated by the standardized data collection and thorough quality control applied within the VIIH

[DOI] [PubMed] [Google Scholar] 53.Cao C., OBrien K.O