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Effects of dapagliflozin compared with sitagliptin and metformin in drug-nave Japanese patients with type 2 diabetes: A 12-week, open-label, randomized, active-controlled trial

The mechanism involved stabilization of the gastric mucosal barrier through enhanced mucus production and reduced oxidative stress markers like malondialdehyde (MDA)

Some researchers report strong effects even at 20 mcg daily, while others require higher doses for noticeable results