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The body compensates by increasing glucose oxidation and, more problematically, by increasing amino acid catabolism, which means breaking down muscle protein for energy

However, the protective effect was strongest in patients with obesity and absent in non-obese patients, strongly suggesting that benefits are heavily confounded by weight loss and metabolic improvement rather than direct gut anti-inflammation (101)

By Wissam Ghusn, MD, Alan De la Rosa, MD, Daniel Sacoto, MD, Lizeth Cifuentes, MD, Alejandro Campos, MD, Fauzi Feris, MD, Maria Daniela Hurtado, MD, PhD, and Andres Acosta, MD, PhD