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In addition, patients with severe liver, kidney problem, uncontrolled diabetes and thyroid problem would be contraindicated as well

In some studies, based on the intraperitoneal infusion of LPS in mice models, it was observed an increase in pro-inflammatory cytokines, such as IL8 and TNF alfa, but also the appearance of autoantibodies against ox LDL, the accumulation of inflammatory infiltrate in the vascular intima, and an increasing aortic atherosclerosis [64]

For most patients asking about peptides to help them sleep, DSIP is the starting point because it targets sleep architecture directly