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Methylcobalamin, a form of B12, is particularly essential for synthesizing neuronal lipids, regenerating axonal nerves, and exerting neuroprotective effects, potentially improving conditions such as Alzheimer's disease, Parkinsonism, and dementia, while also serving as an approved treatment for peripheral neuropathy

EVs were aliquoted and stored in low-protein-binding tubes with 25 mM D(+)-trehalose anhydrous (Chem-Impex International, Wood Dale, IL, USA) at 80 C to be used within 2 weeks

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This cell danger response is an evolutionary adaptation enabled to protect the cells and host from harm (414416)