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Intra-articular delivery of AAV vectors encoding PD-L1 attenuates joint inflammation and tissue damage in a mouse model of rheumatoid arthritis

Increased expression of TIPE1 in DKD leads to the ubiquitinated degradation of PHB2, which disturbs mitochondrial homeostasis, inhibits PINK1/Parkin-mediated mitochondrial autophagy, and encourages EMT and kidney damage

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