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251 Tumor dormancy and reactivation The dormancy and reactivation of long-established disseminated tumor cells (DTCs) in distant organs following primary tumor resection constitute a pivotal factor contributing to tumor recurrence and pose a significant challenge in antitumor therapy

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People were fighting back and forth about this for a long time, until TECOS, the trial with sitagliptin which was the largest and the best of those trials came out with a completely flat result: there was neither an increase nor a decrease in cardiovascular risk