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The potential value of combining these therapies lies in addressing overlapping cardiorenal and metabolic risk pathways as available evidence for dual therapy in HF populations remains limited and is derived largely from subgroup analyses, observational studies, and extrapolation from diabetes or obesity trials rather than dedicated HF randomized trials [24, 25, 27, 30, 50]

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There were three major comparisons performed in this study in order to determine the role of GDH2 and GDH3 in C

Therefore, in order to apply GST3 as a biomarker for neonicotinoid exposure, its gene expression should be a reliable indicator for multiple neonicotinoids and, in particular, for imidacloprid and thiacloprid