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These agents modulate neurotransmission, reduce neuroinflammation and oxidative stress, enhance mitochondrial and neurotrophic function, and improve insulin sensitivity and hypothalamic-pituitary-adrenal (HPA) axis regulation

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Additionally, patients administered L-carnitine had a lower incidence of severe heart failure, left ventricular hypertrophy, arrhythmias, and total cardiac events, including mortality and nonfatal myocardial infarctions, compared to those receiving placebo (Singh et al