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Vitamin Es ability to protect cell membranes makes it valuable for anyone who is not eating an antioxidant-rich diet and who leads an active lifestyle, since physical exertion increases production of free radicals.

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Note that a particular prescription drug for epilepsy control, Depakote (generic: valproic acid), has been found in research to be associated with a significantly increased risk of autism in offspring, when used by mothers during pregnancy

the human signal is uncertain but the drugs are avoided in people with personal or family history of medullary thyroid carcinoma or MEN2