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137 A randomized, placebo-controlled, crossover trial involving 30 subjects with mild sleep complaints found 14 days of treatment with 7.5 mg crocetin, a compound extracted from saffron, increased the intensity of sleep drive as measured with EEG

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Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron

Transitioning from phentermine to tirzepatide A far more common and clinically supported scenario than combining both medications is transitioning from phentermine to tirzepatide