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doi: 10.1113/jphysiol.2002.033811 55 ZhangJJinHZhangWDingCOKeeffeSYeMet al

This lowers blood glucose levels, increases satiety, and reduces food intake

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186 Similarly, lactate from patient-derived GSCs and microglia/macrophages triggers histone Kla, boosting transcriptional upregulation of CD47 in GBM cells, ultimately suppressing phagocytosis and inducing immunosuppressive programs