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This is the first randomized controlled trial of [tirzepatide] and [ixekizumab] in patients with PsA and overweight or obesity that addresses the comprehensive management needs of this patient population, with a positive meaningful impact in multiple domains of PsA disease, including disease control and its comorbidities, Merola and colleagues wrote

DirectMed is $399 per month for 12 months with a one-time initiation fee of $100, plus an annual Prescription Renewal Consultation with a Medical Provider ($99/yr)

And, side-effects appear similar to other incretin-based treatments including nausea, vomiting, diarrhoea or constipation

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