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CAR-T approach is one of the most promising therapies in cancer research but the possibility to extend to senescence field is challenging and could provide a long-term protection against age-related diseases

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This can occur particularly in the early stages of use

The molecule was first identified and studied by the Sikiric research group in Croatia starting in the early 1990s, and the bulk of the preclinical evidence base comes from more than three decades of rat and rodent studies showing consistent tissue-repair, anti-inflammatory, and gastroprotective effects