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Individual tolerance varies considerably based on factors including baseline gastrointestinal function, concurrent medications, dietary habits, and genetic variations in drug metabolism

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Sulforaphane and sulforaphane-nitrile metabolism in humans following broccoli sprout consumption: Inter-individual variation, association with gut Microbiome composition, and differential bioactivity

Earlier studies suggested that bovine lactoferrin inhibited the plasma membrane V-ATPase activity, leading to a decrease in the tumor microenvironment acidity and, ultimately, suppression of cancer metastasis and growth [166, 167]