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A Cochrane Review meta-analysis showed that providing nicotine gum significantly reduced relapse likelihood in individuals who were abstinent at study start and who had previously quit smoking without using formal smoking cessation treatment (2 studies, N = 2,261, risk ratio [RR] = 1.24, 95% confidence interval [CI] = 1.041.47)

Li L, Mu L, Wang X et al (2017) A novel expression vector for the secretion of abaecin in Bacillus subtilis