The longer you have held steady at your goal weight while on medication, the better your chances of maintaining after discontinuation
Specifically, among the 15,264 females on GLP-1 drugs, 1.62% were diagnosed with breast cancer during the study, compared to 2.47% of the 96,382 females who did not use GLP-1 medications
Wegovy contains semaglutide, Saxenda contains liraglutide, and Zepbound contains tirzepatide, which is a dual GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptor agonist
Given that tryptophan is a substrate for SLC6A14, the inhibitor -methyltryptophan (-MT) suppresses the growth of SLC6A14-positive breast cancer, PDAC, and CRC cells but not SLC6A14-negative cells 107,108,109