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Stage 4: Approaching the beyond-use date As you approach the BUD, the margin for storage errors shrinks

To assess the association of semaglutide with incident CUD, the study population included 587,849 patients with T2D who had active medical encounters for T2D during 12/20175/2021, were for the first time prescribed semaglutide (Ozempic) or non-GLP1-1RA anti-diabetes medications (new-user design) during 12/20175/2021(index event), had no diagnosis of CUD on or before the index event and had a diagnosis of at least one of obesity-associated comorbidities (T2D, hypertension, hypercholesterolemia, hyperlipidemia, heart diseases, stroke) on or before the index event

You can change the day of the week that you take your semaglutide as long as it has been 2 or more days (48 or more hours) since you injected your last shot

For OCT imaging, we used the same spectral-domain OCT (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany