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Treatment with L-Carnitine (300 mg/kg) and alpha-lipoic acid (100 mg/kg) for 28-30 days in aged rats restores activities of succinate dehydrogenase, malate dehydrogenase, -ketoglutarate dehydrogenase, isocitrate dehydrogenase, and respiratory complexes I-IV to near-normal levels, indicating enhanced mitochondrial energy-producing capacity
[DOI] [PubMed] [Google Scholar] 121.Carlberg C.E., Mller L., Paakki P., Kantola M., Stockmann H., Purkunen R., Wagner P., Lauper U., Kaha M., Elovaara E., et al
In addition, proteomic studies highlight the complex interplay between depression and comorbid conditions such as diabetes, emphasizing the importance of accounting for a patients overall health status during diagnosis and treatment planning [448]
Zhang, Fu 2013
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