can't sleep on semaglutide Insomnia: Does Semaglutide Affect Sleep? Semaglutide Weight Loss and Sleep:

That mechanism doesn't change based on whether the semaglutide was manufactured by a pharmaceutical company or compounded by a licensed pharmacy

Psychological factors , including unaddressed emotional eating, binge eating disorder, or using food as a coping mechanism for stress or low mood, may also limit weight loss despite reduced physiological hunger

these factors make GLP-1 RAs an alternative initial treatment option, with or without metformin based on glycemic needs, in T2DM patients with indicators of high-risk or established heart failure (HF) or CKD who cannot tolerate an SGLT2 inhibitor

Take home message Most common painkillers are safe to take alongside Wegovy