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J Biomed Mater Res A 103(3):12381245 Patel S, Jung D, Yin PT, Carlton P, Yamamoto M, Bando T, Sugiyama H, Lee KB (2014) NanoScript: a nanoparticle-based artificial transcription factor for effective gene regulation

SQS is an enzyme involved in the synthesis of cholesterol, which leads to the depletion of the endogenous antioxidant Coenzyme Q10 (CoQ10), a non-steroidal metabolite in the glutaric acid pathway