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Layered Tissue Targeting : Each facial tissue layer receives appropriate treatment: Deep planes: Biostimulators and ultrasound technologies Mid-level: Strategic filler placement and RF technologies Superficial: Laser treatments and skincare 2

This is a high-risk population, and historically weve had limited data to guide treatment decisions, said Amy Sheer, MD, associate professor of medicine and director of the Obesity Medicine Fellowship program at the University of Florida

Then, they were randomly divided into the following 6 experimental groups (Additional file 1): 1

Visual inspection is your first-line quality check