Excipient studies on lyophilized rhGH show that sugar and polyol stabilizers (mannitol, sucrose, trehalose) protect the protein's secondary structure and limit aggregation in the dry state by satisfying water-binding sites and stabilizing the amorphous matrix around the protein (Costantino et al., 1998)
Better sleep lowers cortisol, a stress hormone closely linked to abdominal fat and cravings
Targeting both receptors simultaneously, as with tirzepatide, leverages these complementary effects, enhancing insulin secretion [3], reducing appetite, improving insulin sensitivity, and supporting weight loss more effectively than single receptor agonists
Retrospective studies have demonstrated that some beneficial polyphenols have the capacity to increase the activity of CBS [14, 15]