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Dietary lipids differentially shape nonalcoholic steatohepatitis progression and the transcriptome of Kupffer cells and infiltrating macrophages

This represents a direct pharmacological effect rather than an indirect consequence of diabetes control

The spin-trap agent NXY-059 has shown to reduce stroke impairment (241) and to confer protection toward tPA-induced hemorrhage (242) in animal models of stroke

Natriuresis and Diuresis Studies in people living with T2DM and obesity have shown that GLP-1 RA administration can induce diuresis and natriuresis [110, 111] that likely contribute to the renoprotective effects of GLP-1 RA