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In the pre-specified in-study analysis based on pooled 9 mg and 12 mg retatrutide groups, 44 participants receiving retatrutide experienced a MACE-5 event, defined as all-cause death, myocardial infarction, stroke, heart failure event, or coronary revascularization, compared with 52 participants receiving placebo, corresponding to a hazard ratio of 0.82 (95% CI: 0.55-1.22)

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If you've never heard of food noise before, it's those nagging thoughts about food that constantly make you daydream about your next meal or snack., While many people get a reprieve when they take GLP-1s, that noise often returns when they stop taking the medication, says Steph Wagner, M.S., RDN, CSOWM, LD