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While standard L-carnitine supplements exist, they have limited ability to cross the blood-brain barrier where much of the cognitive benefits occur

1 Asymptomatic autoimmune gastritis likely precedes gastric atrophy by 10 to 20 years, followed by the onset of iron-deficiency anemia that occurs as early as 20 years before vitamin B 12 deficiency pernicious anemia

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The wild-type and the engineered strains were cultured in bioreactors with ammonium or nitrate as the nitrogen source