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doi: 10.3389/fonc.2025.1581951 Received 23 February 2025 Accepted 29 April 2025 Published 04 June 2025 Volume 15 - 2025 Edited by Weiling Li, Dalian Medical University, China Reviewed by Liewei Wen, Jinan University, China Xinghua Yu, Zhejiang University, China Updates Copyright 2025 Liu, Jing, Chen, Sun, Xu, Liang, Liu, Zhang and Liu