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Then they were seated in a wheelchair to have their calf muscles electrically stimulated while force output by the muscles was recorded

In fact, gene expression proves this to be true

proposed that the anti-arthritic effects of NOR were attributed to the restoration of aberrant lipid metabolism, as demonstrated in detail by the upregulation of carnitine palmitoyltransferase 1 expression and downregulation of fatty acid synthase expression by NOR in the spleen and synovial tissues of CIA rats ( Isosilybin A, a major bioactive constituent of silymarin, is a partial PPAR agonist that modifies abnormalities of lipid metabolism and stimulates cholesterol efflux from THP-1 macrophages (Zhang et al., 2017) is medications with PPAR agonist characteristic that can alleviate RA

10.3390/jcm1109242135566547 135 Pan G, Liu Y, Yu L, et al