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Severity of airflow limitation is associated with severity of airway inflammation in smokers

Mirren following in the sturdy, lace-up work shoes of previous Meir actors like Anne Bancroft, Judy Davis and Tovah Feldshuh does an admirable job lurching from war meeting to war meeting and tossing off great lines like: All political careers end in failure and I will not be taken alive. (Mirren has so far largely avoided the criticism that Bradley Cooper has faced for playing Leonard Bernstein, though they are both non-Jews using prosthetics.) But the script gives Mirren little insight into what is going on inside Meir

Other symptoms that often accompany BMS include: A scalded or sore feeling in the mouth An unpleasant metallic or bitter taste