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We then immunostained the brain sections with anti-Arc and -Prox1 antibodies to detect Arc expressing granule cells and quantified the density of Arc+/Prox1+ cells ( n = 9 novel environment control, 6 home-cage control, 10 novel environment DG-NR1KO, 10 home-cage DG-NR1KO mice

Epithelial-mesenchymal transition Epithelial-mesenchymal transition (EMT) is a crucial mechanism closely associated with the ability of cancer cells to invade and metastasize distantly (Wang et al

53,186,221 Together, these pathways coordinate the cellular transformations necessary for an effective regenerative response

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