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More recently, a mitochondrial targeted antioxidant Mito-Tempo was reported to protect against AILI even at 3 h post-treatment of APAP compared with NAC alone, suggesting it as a potential therapeutic option for patients at late phase in APAP poisoning [29]

Instead of blocking pain signals, its investigational focus is on healing the underlying injury and reducing the inflammation that causes the pain in the first place, which is a fundamentally different approach

doi: 10.3389/fcvm.2021.803979 Received 28 October 2021 Accepted 29 November 2021 Published 20 December 2021 Volume 8 - 2021 Edited by Michael Lichtenauer, Paracelsus Medical University, Austria Reviewed by Bernhard Wernly, Paracelsus Medical University, Austria

Nat Med (1998) 4(12):13716