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At week 26, the primary HbA1c endpoint was missing for 5.8%, 6.2% and 4.5% of patients randomized to RYBELSUS 7 mg, RYBELSUS 14 mg and sitagliptin 100 mg, respectively

1 Separately, Novo Nordisk has also submitted an application in the US for a once-daily oral formulation of semaglutide under the trade name Wegovy for the treatment of obesity

Discussion Semaglutide has proven to be a powerful and effective treatment for obesity and T2D, offering positive effects on metabolic issues linked to steatotic liver disease, as well as improving cardiovascular and renal outcomes, all without elevating cancer risk