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Acknowledgements The authors are thankful to the Plant Physiology and Molecular Systematics and Applied Ethnobotany Lab

Due to its vasodilatory action, nicotinic acid (niacin) should be used with caution in those patients with uncorrected hypotension (or predisposition to orthostatic hypotension), acute myocardial infarction, or unstable angina, particularly when vasodilator medications such as nitrates, calcium channel blockers, or adrenergic blocking agents are coadministered (see Drug Interactions)

Absent Exercise-Induced Improvements in Fat Oxidation in Women With Polycystic Ovary Syndrome After High-Intensity Interval Training

However, this process is non-selective and influenced by regional differences in receptor density, blood flow, and hormonal sensitivity