retatrutide to lose weight VisualAbstract: reduces body by 17.5% in patients with obesity Retatrutide vs Tirzepatide vs Semaglutide

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The use of GLP-1 receptor agonists has been associated with an increased risk of gallbladder disease in some studies, though the evidence is not yet conclusive. Novo Nordisk, Ozempic Prescribing Information Potential Mechanisms of Interaction The exact ways GLP-1 receptor agonists affect gallbladder function are complex

Diabetes Care 36 Suppl 2: S245-252, 2013

Implications for insurers Insurers should consider the impact of AOMs across their business: Assess how AOMs may impact protection, morbidity, and longevity experience Review trend assumptions to identify whether changes are needed Establish processes to keep on top of this fast-moving space Consider new lapse risks Assess how AOMs might affect underwriting and claims Insured impacts and reviewing trend assumptions Insurers should consider adjustments to their specific mortality and morbidity improvement assumptions to reflect AOMs