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Many of these compounds efficacy and safety remain incompletely and properly evaluated in humans, and continue to be used outside conventional medical frameworks, increasingly marketed with the language of longevity, optimization, and self-care

J Clin Med 12(23):7221

Although the impact of GLP-1RAs on pancreatic cancer risk remains controversial, emerging evidence suggests that chronic low-grade inflammation and proliferative changes may constitute key pathophysiological mechanisms underlying pancreatic cancer development in patients receiving GLP-1RA therapy [8]