Along with these observations, calcitriol is known of influencing immunity regarding anti-inflammatory responses, tolerogenic actions and the prevention of immune overstimulation [68]
This makes the combination appealing for patients who want a more supportive, systems-based approach to aging, recovery, and performance
Furthermore, we evaluate emerging therapeutic strategies-ranging from iron chelation and radical-trapping antioxidants to GPX4-modulating agents and advanced nanomedicine-based delivery platforms-and critically appraise the landscape of candidate biomarkers indispensable for clinical translation, encompassing circulating lipid peroxidation products, iron metabolism indices, regulatory non-coding RNAs, and advanced imaging surrogates.By integrating mechanistic insights with translational perspectives, this Review positions ferroptosis as both a fundamental driver of cardiovascular pathology and a promising frontier for the development of precision diagnostics and targeted therapies aimed at mitigating the global burden of CVD
red meat has the highest concentration, with poultry and fish containing much less