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Degner NR, Wang JY, Golub JE, Karakousis PC

Interstitial cystitis: In a trial of 12 women (ages 39-76) with moderate to severe interstitial cystitis unresponsive to conventional treatment, a single 10 mg BPC-157 injection led to complete symptom resolution in 10 patients and 80% improvement in 2, with no reported adverse effects (18) Knee pain: A retrospective study found that 11 of the 12 patients (91.6%) receiving BPC 157 as an intra-articular injection had significant improvement in knee pain, whereas 1 patient (8.3 %) had no improvement (19) Efficacy of BPC 157 Delivery Methods BPC-157 can be administered orally, topically, or via injection

doi: 10.3389/fphar.2024.1412245 Received 04 April 2024 Accepted 24 June 2024 Published 18 July 2024 Volume 15 - 2024 Edited by Irina Ielciu, University of Medicine and Pharmacy Iuliu Hatieganu, Romania Reviewed by Javad Mottaghipisheh, Swedish University of Agricultural Sciences, Sweden Shaymaa Mahmoud, University of Menoufia, Egypt Ufuk Koca alilkan, Gazi University, Trkiye Aida Abd El-Wahed, Agricultural Research Center, Egypt Gandhi Radis Baptista, Federal University of Ceara, Brazil Updates Copyright 2024 Sadek, Shib, Taher, Rashed, Shukry, Atia, Taymour, El-Nablaway, Ibrahim, Ramadan, Abdelkader, Abdo, Imbrea, Pet, Ali and Abdeen