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VEGF-R2 axis / local angiogenesis BPC-157 upregulates VEGF-R2 (KDR) receptor expression on vascular endothelium at the lesion site, triggering early neoangiogenesis required for tendon and ligament repair (Sikiric 2018, successive reviews)
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Peptides with cationic motifs utilize electrostatic interactions to target and bind negatively charged phospholipids in cell membranes, thereby facilitating their entry into cells 55
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors
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